Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transient retinofugal pathways in the developing chick.

S C McLoon, R D Lund

    Experimental Brain Research
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    MHC antigen expression and cellular response in spontaneous and induced rejection of intracerebral neural xenografts in neonatal rats.

    Restorative neurology and neuroscience·2011
    Same author

    Retinal ganglion cell population in adult albino and pigmented mice: a computerized analysis of the entire population and its spatial distribution.

    Vision research·2009
    Same author

    Intraretinal processing following photoreceptor rescue by non-retinal cells.

    Vision research·2009
    Same author

    A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats.

    Vision research·2008
    Same author

    Most superficial sublamina of rat superior colliculus: neuronal response properties and correlates with perceptual figure-ground segregation.

    Journal of neurophysiology·2007
    Same author

    EphA5 and ephrin-A2 expression during optic nerve regeneration: a 'two-edged sword'.

    The European journal of neuroscience·2007

    Early chick embryo development reveals a transient ipsilateral retinal projection to visual nuclei. This temporary pathway disappears by day 15, coinciding with retinal ganglion cell death.

    Area of Science:

    • Neuroscience
    • Developmental Biology
    • Ophthalmology

    Background:

    • The central retinal projections guide visual information processing.
    • Understanding early visual pathway development is crucial for identifying developmental abnormalities.

    Purpose of the Study:

    • To investigate the presence and characteristics of a transient ipsilateral retinal projection in normal chick embryos.
    • To determine if this projection is a normal developmental feature or an anomaly.

    Main Methods:

    • Utilized anterograde transport of horseradish peroxidase (HRP) with tetramethyl benzidine (TMB) chromogen.
    • Employed degeneration techniques to trace retinal axon distribution.
    • Examined chick embryos at successive developmental stages (6-16 days of incubation).

    Related Experiment Videos

    Main Results:

    • A transient ipsilateral retinal projection to primary visual nuclei was observed in embryos between 6 and 12 days of incubation.
    • A projection into the contralateral optic nerve was also detected during this period.
    • These anomalous projections disappeared by embryonic day 15, coinciding with significant retinal ganglion cell apoptosis.

    Conclusions:

    • Chick embryos normally exhibit a transient ipsilateral retinofugal projection early in development.
    • The observed ipsilateral projection may contribute to the apparent ipsilateral retinofugal projection seen after embryonic enucleation in chicks, similar to findings in rats.