Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Natural killer cells.

R B Herberman

    Hospital Practice (Hospital Ed.)
    |April 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Natural killer (NK) cells, a newly identified immune effector, show potential for clinical use in antitumor therapy due to their unique activity.

    Related Experiment Videos

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Tumor immunology.

    JAMA·1992
    Same author

    The T-cell receptor V beta gene usage in tumor-infiltrating lymphocytes and blood of patients with hepatocellular carcinoma.

    Cancer research·1992
    Same author

    Receptors for interleukin 2 on human squamous cell carcinoma cell lines and tumor in situ.

    Cancer research·1992
    Same author

    Nongranular proteolytic enzymes of rat IL-2-activated natural killer cells. I. Subcellular localization and functional role.

    Journal of immunology (Baltimore, Md. : 1950)·1992
    Same author

    Two new human cholangiocarcinoma cell lines and their cytogenetics and responses to growth factors, hormones, cytokines or immunologic effector cells.

    International journal of cancer·1992
    Same author

    Tissue distribution of adoptively transferred adherent LAK cells: role of the route of administration.

    Natural immunity·1992
    Same journal

    The Current Status of Liver Transplantation.

    Hospital practice (Hospital ed.)·2011
    Same journal

    Fever of unknown origin: diagnostic principles.

    Hospital practice (Hospital ed.)·1982
    Same journal

    Biology of C-reactive protein and the acute phase response.

    Hospital practice (Hospital ed.)·1982
    Same journal

    A pneumonia and fever that defied treatment.

    Hospital practice (Hospital ed.)·1982
    Same journal

    Pain, ascites in a woman with mitral stenosis.

    Hospital practice (Hospital ed.)·1982
    Same journal

    Preterm births reduced in prophylactic program.

    Hospital practice (Hospital ed.)·1982
    See all related articles

    Area of Science:

    • Immunology
    • Cellular Biology
    • Cancer Research

    Background:

    • Natural killer (NK) cells are a class of lymphocytes.
    • NK cells are characterized by their ability to induce lysis of target cells without prior sensitization.
    • They represent a crucial component of the innate immune system.

    Purpose of the Study:

    • To introduce Natural Killer (NK) cells as a novel immunopathologic effector.
    • To discuss the potential clinical applications of NK cell activity in cancer therapy.

    Main Methods:

    • Review of existing literature on NK cell function and immunology.
    • Analysis of NK cell mechanisms in comparison to other immune effectors.

    Main Results:

  • NK cells possess cytotoxic activity without prior sensitization.
  • Their unique properties distinguish them from other immune cells like T cells and K cells.
  • Conclusions:

    • The understanding of NK cell biology has advanced significantly.
    • NK cell activity holds promise for clinical exploitation in the development of novel antitumor therapies.