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Related Experiment Videos

Canine intestinal carcinoids.

G P Sykes, B J Cooper

    Veterinary Pathology
    |March 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Malignant intestinal carcinoids were diagnosed in three aged dogs, with two tumors in the rectum and one in the cecocolic junction. Electron microscopy confirmed these aggressive neoplasms by identifying secretory granules.

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    Area of Science:

    • Veterinary Pathology
    • Oncology
    • Gastroenterology

    Background:

    • Intestinal carcinoids, a type of neuroendocrine tumor, are rare in dogs.
    • Aged dogs are more susceptible to various neoplastic conditions.
    • Understanding the characteristics of canine intestinal carcinoids is crucial for diagnosis and treatment.

    Observation:

    • Three aged dogs presented with intestinal neoplasms.
    • Two tumors were located in the rectum, and one was found at the cecocolic junction.
    • Histologic examination indicated malignant potential for all three tumors.

    Findings:

    • Amyloid deposition was observed in both rectal carcinoid tumors.
    • Electron microscopy revealed electron-dense intracytoplasmic secretory granules in neoplastic cells, confirming the carcinoid diagnosis.

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  • All identified intestinal carcinoids exhibited malignant features.

    • Implications:

    • This study highlights the occurrence and malignant nature of intestinal carcinoids in aged dogs.
    • The findings contribute to the understanding of canine neuroendocrine tumors.
    • Accurate diagnosis using histology and electron microscopy is vital for managing these rare canine cancers.