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[An improved mouse metabolism cage and its performance tests (author's transl)]
Jikken Dobutsu. Experimental Animals
|January 1, 1982
Summary
This study introduces an improved mouse metabolism cage designed for accurate urine volume measurement. The novel design minimizes animal stress and prevents fecal contamination, ensuring reliable research data.
Area of Science:
- Physiology
- Animal models
- Laboratory equipment
Context:
- Metabolism cages are essential for studying physiological processes in rodents.
- Conventional cages often suffer from fecal contamination and animal stress, compromising data accuracy.
- Accurate measurement of urine output and intake is critical for metabolic research.
Purpose:
- To describe an improved mouse metabolism cage design.
- To enhance the accuracy of urine volume measurement.
- To reduce animal stress and prevent contamination in metabolism studies.
Summary:
- The improved cage features a semi-level top surface for reduced animal instability and stress.
- A steeper gradient on the separator's surface, a shortened collection tail, and a water leak receptacle prevent contamination.
- An insulator at the bottom prevents animal escape, ensuring complete containment.
Impact:
- Facilitates more accurate physiological and metabolic research in mice.
- Reduces potential errors in urine analysis due to contamination.
- Enhances animal welfare by minimizing stress during metabolic studies.