Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Percutaneous transhepatic biliary drainage for obstructive jaundice.

G R Faithfull, R C Smith, N A Manap

    The Medical Journal of Australia
    |March 20, 1982
    PubMed
    Summary

    Percutaneous transhepatic biliary drainage (PTBD) offers a non-surgical solution for biliary obstruction, improving patient condition before surgery or providing palliative care for advanced malignancy, thus avoiding high-risk operations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Occupational radiation exposure to anesthetists from fluoroscopic projections during orthopedic operative procedures.

    La Clinica terapeutica·2014
    Same author

    Transgene delivery of plasmid DNA to smooth muscle cells and macrophages from a biostable polymer-coated stent.

    Gene therapy·2003
    Same author

    PDGF-BB enhances expression of, and reduces adhesion to, laminin-5 in vascular smooth muscle cells.

    Biochemical and biophysical research communications·2002
    Same author

    Tissue-specific expression of an anti-proliferative hybrid transgene from the human smooth muscle alpha-actin promoter suppresses smooth muscle cell proliferation and neointima formation.

    Gene therapy·2002
    Same author

    Gastric lipoma causing gastroduodenal intussusception.

    International journal of clinical practice·2002
    Same author

    Local gene delivery to the vessel wall.

    Acta physiologica Scandinavica·2001

    Area of Science:

    • Interventional Radiology
    • Hepatobiliary Medicine
    • Oncology

    Background:

    • Extrahepatic biliary obstruction presents significant challenges in patient management.
    • High-risk surgery for biliary obstruction is associated with considerable mortality and morbidity.
    • Percutaneous Transhepatic Biliary Drainage (PTBD) has emerged as a non-surgical alternative.

    Observation:

    • PTBD serves as a temporary measure to stabilize patients pre-operatively.
    • It allows for further diagnostic investigations.
    • For advanced malignancy, long-term PTBD can be a definitive palliative treatment, obviating surgery.

    Findings:

    • Preoperative PTBD in ten patients significantly reduced serum bilirubin (P<0.01), alkaline phosphatase (P<0.05), and LDH (P<0.01) within 12 days.

    Related Experiment Videos

  • This preoperative intervention led to minimal operative morbidity and mortality.
  • Twelve patients with advanced malignancy received long-term PTBD, with three experiencing good palliation for 12-14 months.

    • Implications:

    • PTBD effectively manages biliary obstruction, improving preoperative status and offering palliative care.
    • It presents a viable alternative to high-risk surgery in select patient populations.
    • The procedure demonstrates potential for significant symptom relief and improved quality of life in advanced malignancy.