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Development dysphasia and electroencephalographic abnormalities.

M Maccario, S J Hefferen, S J Keblusek

Developmental Medicine and Child Neurology

|April 1, 1982

Summary

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Severe language delay in young children was linked to abnormal electroencephalograms (EEGs), even without seizures. Postmaturity may be a contributing factor to these neurological and language issues.

Area of Science:

Neuroscience
Developmental Pediatrics
Clinical Electrophysiology

Background:

Investigating the link between severe language delay and electroencephalogram (EEG) abnormalities in young children.
Examining children with dysphasic errors and markedly abnormal EEGs, with limited history of febrile seizures.

Observation:

Seven children (6 boys, 1 girl) aged 2y 7m to 5y 6m presented with severe language delay.
Abnormal EEGs showed spike-wave or sharp wave discharges, unaffected by anticonvulsants.
Normal motor development, no dysmorphic features, normal neurological exams, and normal non-verbal intelligence.

Findings:

Markedly abnormal EEGs were present in all children, despite only two having febrile seizures.
EEG abnormalities persisted and were unresponsive to anticonvulsant treatment.

Related Experiment Videos

Five of seven cases had a history of postmaturity, suggesting potential perinatal etiological factors.

Implications:

Suggests an underlying electrophysiological disturbance as the cause of language deficits and EEG abnormalities.
Highlights the potential role of perinatal events, such as postmaturity, in the etiology of these neurodevelopmental disorders.
Underscores the importance of EEG evaluation in children with unexplained severe language delay.