Related Experiment Video

Updated: Aug 18, 2026

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
10:22

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity

Published on: September 16, 2011

The role of basophils in asthma. I. Sodium cromoglycate on histamine release and content

M K Church

    Clinical Allergy
    |May 1, 1982
    PubMed

    More Related Videos

    Basophil Activation Test for Allergy Diagnosis07:22

    Basophil Activation Test for Allergy Diagnosis

    Published on: May 31, 2021

    Humanized Mediator Release Assay as a Read-Out for Allergen Potency10:22

    Humanized Mediator Release Assay as a Read-Out for Allergen Potency

    Published on: June 29, 2021

    Related Concept Videos

    Asthma: Pathogenesis and Management01:20

    Asthma: Pathogenesis and Management

    Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
    Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
    Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

    Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

    Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
    ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
    Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

    Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

    Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
    Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
    Asthma-II: Pathophysiology and Classification01:26

    Asthma-II: Pathophysiology and Classification

    Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
    Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
    Critical processes in asthma pathophysiology include:
    Asthma-IV: Diagnostic and Management01:30

    Asthma-IV: Diagnostic and Management

    The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
    Clinical Assessment for Asthma:
    This is the first step in diagnosing and managing asthma. It includes:
    Asthma I: Introduction01:28

    Asthma I: Introduction

    Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...