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Serological diversity in Haemophilus somnus.
Journal of Clinical Microbiology
|June 1, 1982
Summary
Serological analysis of Haemophilus somnus strains revealed distinct American and Swiss antigen sets, alongside common antigens. These combinations form four agglutination groups, correlating with geographical origin.
Area of Science:
- Veterinary Microbiology
- Immunology
- Bacteriology
Background:
- Haemophilus somnus is a significant pathogen in livestock.
- Understanding the antigenic diversity of H. somnus is crucial for diagnostics and vaccine development.
Purpose of the Study:
- To investigate the serological relationships among 46 Haemophilus somnus strains.
- To identify antigenic components and their geographical distribution within H. somnus populations.
Main Methods:
- Agglutination tests were performed on 46 H. somnus strains.
- Agglutinin adsorption procedures were utilized to differentiate antigenic specificities.
- Sera from American and Swiss isolates were used to analyze cross-reactivity.
Main Results:
- Sera against representative American and Swiss isolates agglutinated all tested strains.
- Antigen adsorption studies indicated the presence of at least three antigen sets: American, Swiss, and common.
- Four distinct agglutination groups were identified, primarily reflecting the geographical origin of the strains.
Conclusions:
- Haemophilus somnus possesses geographically distinct and common antigenic factors.
- The identified antigenic groups suggest a basis for serotyping H. somnus strains.
- Geographical origin is a significant factor in H. somnus antigenic variation.