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Vitamin C and cancer: an overview
International Journal for Vitamin and Nutrition Research. Supplement = Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Supplement
|January 1, 1982
Summary
Supplemental ascorbic acid (vitamin C) may enhance cancer resistance by supporting immune function and collagen production. Clinical evidence suggests vitamin C has therapeutic value in cancer treatment, potentially becoming a standard part of care.
Area of Science:
- Oncology
- Nutritional Science
- Immunology
Background:
- Host resistance significantly influences cancer outcomes.
- Nutritional factors, particularly ascorbic acid, are increasingly recognized for their role in cancer resistance.
- Ascorbic acid's functions include stabilizing ground substance and enhancing collagen encapsulation.
Purpose of the Study:
- To review the therapeutic potential of supplemental ascorbic acid in cancer treatment.
- To evaluate the evidence supporting ascorbic acid's role in host resistance to neoplasia.
Main Methods:
- Review of clinical trials on supplemental ascorbate in cancer treatment over the last decade.
- Analysis of ascorbic acid's known mechanisms in host resistance, including immune modulation and cytotoxic effects.
Main Results:
- Ascorbic acid supports host resistance through mechanisms like stabilizing ground substance, enhancing collagen production, and modulating immune responses (cell-mediated, humoral, interferon production).
- Emerging evidence suggests ascorbate may selectively target malignant cells.
- Clinical trials reviewed indicate a supportive role for supplemental ascorbate in cancer therapy.
Conclusions:
- Supplemental ascorbic acid demonstrates therapeutic value in cancer treatment.
- Ascorbic acid's multifaceted roles in host resistance and potential direct anti-cancer effects support its use.
- It is predicted that supplemental ascorbate will become a standard component of comprehensive cancer treatment regimens.