[Exposure to heterologous proteins in the initial stages of experimental atherosclerosis in rabbits]

Intravenous preinjections of rabbits with large doses of bovine serum albumin accelerated the development of experimental atherosclerosis, while subcutaneous immunization with less doses of antigen did not affect the process. Preliminary immunization of rabbits with large doses of human gamma-globulin did not accelerate the development of atherosclerosis, whereas immunization with low doses (the total dose 150 mg) even inhibited its development.