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Updated: Aug 15, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Intrahisian functional bundle branch block

Y Iesaka, J J Rozanski, T Pinakatt

    Pacing and Clinical Electrophysiology : PACE
    |September 1, 1982
    PubMed

    Insights

    Functional complete left bundle branch block can result from longitudinal dissociation within the His bundle. This finding clarifies the localized cause of this specific cardiac conduction abnormality.

    Area of Science:

    • Cardiology
    • Electrophysiology
    • Cardiac Anatomy

    Background:

    • Left bundle branch block (LBBB) is a common cardiac arrhythmia.
    • Understanding the precise anatomical location of block is crucial for diagnosis and treatment.
    • The His bundle is a key component of the cardiac conduction system.

    Observation:

    • A case study of a patient presenting with functional complete left bundle branch block was analyzed.
    • Diagnostic localization techniques pinpointed the block to the His bundle region.

    Findings:

    • The observed functional complete left bundle branch block was attributed to longitudinal dissociation within the His bundle.
    • This suggests a specific mechanism for LBBB not previously emphasized.

    Implications:

    • This case highlights the His bundle's susceptibility to localized conduction defects.
    • Findings contribute to a more nuanced understanding of LBBB pathophysiology.
    • May inform future diagnostic and therapeutic strategies for His bundle-related arrhythmias.

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