Related Experiment Video

Updated: Aug 13, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
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Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization

Published on: February 3, 2013

An idiotypic determinant formed by both immunoglobulin constant and variable regions

G Morahan, C Berek, J F Miller

    Nature
    |February 24, 1983
    PubMed
    Summary

    Antibody idiotypes, like the T15 system for phosphorylcholine (PC) binding, can involve immunoglobulin constant regions. This finding suggests isotype-restricted idiotopes may regulate antibody responses.

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