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Related Experiment Videos

[Experience with a blood component program in surgical hemotherapy].

P Lundsgaard-Hansen

    Folia Haematologica (Leipzig, Germany : 1928)
    |January 1, 1982
    PubMed
    Summary
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    Vox sanguinis·1992

    The University Hospital in Berne uses a component blood transfusion system, transfusing 85% red cell concentrates. This method, utilizing critical blood component levels, showed no adverse effects in 372 surgical patients.

    Area of Science:

    • Transfusion Medicine
    • Surgical Patient Management
    • Blood Component Therapy

    Context:

    • The University Hospital in Berne has utilized a component blood transfusion concept for six years.
    • Eighty-five percent of red blood cell units are transfused as high-hematocrit concentrates (70%), with 15% as fresh whole blood.
    • This approach is applied to surgical patients, leveraging distinct critical levels of blood volume, hematocrit, total serum protein, coagulation factors, and platelets.

    Purpose:

    • To investigate the efficacy and safety of a component blood transfusion system in surgical patients.
    • To assess the impact of transfusing high-hematocrit red cell concentrates on postoperative outcomes.
    • To determine if this system affects the demand for human plasma protein solutions.

    Summary:

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    • A component blood transfusion system, featuring 85% high-hematocrit red cell concentrates and a colloid plasma substitute, was implemented at the University Hospital in Berne.
    • A retrospective study of 372 patients found no negative impact on postoperative course.
    • The system did not increase demand for plasma protein solutions in its first 4.5 years and can support national albumin and factor VIII needs.

    Impact:

    • Demonstrates a safe and effective alternative for red blood cell transfusion in surgical settings.
    • Suggests that component therapy can be managed without increasing reliance on plasma-derived products.
    • Highlights the potential for blood donation systems to meet demands for various blood components, including albumin and factor VIII.