Related Experiment Videos
Use of plasma volume substitutes and plasma in developing countries
Bulletin of the World Health Organization
|January 1, 1983
Summary
Crystalloids like saline and dextrose are vital for treating shock and hemorrhage in developing nations due to their low cost and local production. Plasma substitutes and fresh frozen plasma are secondary priorities for specific conditions.
Area of Science:
- Emergency Medicine
- Critical Care
- Global Health
Background:
- Plasma and plasma substitutes are crucial for managing hemorrhage and shock.
- Peripheral health facilities in developing countries face unique challenges in fluid resuscitation.
- Availability and cost-effectiveness are key considerations for treatment options.
Purpose of the Study:
- To review the role of various plasma and plasma substitutes in treating hemorrhage and shock.
- To assess the suitability of different fluid therapies for resource-limited settings.
- To provide recommendations for peripheral health facilities in developing countries.
Main Methods:
- Review of existing literature on plasma and plasma substitutes.
- Analysis of fluid therapy options based on cost, stability, and local production feasibility.
- Focus on applications in peripheral health facilities in developing countries.
Main Results:
- 0.9% saline and 5-6% dextrose are highly recommended due to local production ease, stability, and cost-benefit ratio.
- Colloid plasma substitutes are a secondary priority.
- Fresh frozen or fresh liquid plasma is valuable for hemostatic issues and severe burns, offering a broad spectrum of components and local production viability.
Conclusions:
- Saline and dextrose solutions are essential first-line treatments in developing countries.
- A limited supply of colloid plasma substitutes should be available.
- Fresh frozen plasma is important for specific indications like hemostatic derangements and severe burns.