[Effect of enkephalin analogs on various digestive functions during restriction of motor activity]

Rats were exposed to 7-day hypokinesia and the effect of an enkephalin analog on the secretion of pepsin, amylase, the shape of the glycemic curve and the secretion of gastrointestinal hormones, gastrin and insulin, was investigated. The hypokinetic exposure increased pepsin in the gastric mucosa and amylase in the pancreas, and decreased glycemia and insulin secretion. The analog normalized exo- and endocrine function of the pancreas and the shape of the glycemic curve.