Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic dopaminergic sensitivity after Sydenham's chorea.

P A Nausieda, L A Bieliauskas, L D Bacon

    Neurology
    |June 1, 1983
    PubMed
    Summary

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Psychological depression in the elderly in medical/rehabilitation/nursing care settings.

    NeuroRehabilitation·2014
    Same author

    Failed back surgeries and minnesota multiphasic personality inventory (MMPI) profiles.

    Journal of clinical psychology in medical settings·2013
    Same author

    On perhaps becoming what you had previously despised: Psychologists as prescribers of medication.

    Journal of clinical psychology in medical settings·2013
    Same author

    Could versus should: A reply to Sammons.

    Journal of clinical psychology in medical settings·2013
    Same author

    Shifted inferior frontal laterality in women with major depressive disorder is related to emotion-processing deficits.

    Psychological medicine·2013
    Same author

    Genetics and vaccine efficacy: host genetic variation affecting Marek's disease vaccine efficacy in White Leghorn chickens.

    Poultry science·2010

    Patients with a history of Sydenham's chorea may experience persistent sensitivity to certain medications, leading to adverse reactions and potential psychological difficulties. This sensitivity is linked to dopaminergic activity.

    Area of Science:

    • Neuroscience
    • Psychiatry
    • Movement Disorders

    Background:

    • Sydenham's chorea (SC) is a childhood autoimmune disorder.
    • Survivors may experience long-term neurological and psychological effects.
    • Dopaminergic system alterations are implicated in choreiform disorders.

    Purpose of the Study:

    • To investigate psychometric performance and drug-induced choreic reactions in SC patients.
    • To identify potential links between MMPI profiles and adverse drug responses.
    • To explore the hypothesis of persistent central dopaminergic hypersensitivity in SC survivors.

    Main Methods:

    • Assessed psychometric performance using the Minnesota Multiphasic Personality Inventory (MMPI) mini-mult.
    • Evaluated drug-induced choreic reactions in patients with a history of SC.
    Keywords:
    ChoreaContraceptionContraceptive AgentsContraceptive Agents, FemaleContraceptive Methods--side effectsDiseasesFamily PlanningOral Contraceptives--side effectsPsychological FactorsPsychologyReproductive Control AgentsSigns And SymptomsTesting

    Related Experiment Videos

  • Analyzed correlations between MMPI scores and reported adverse reactions.

    • Main Results:

    • Action tremor, motor signs, and residual chorea were prevalent.
    • Half of the patients reported adverse choreic reactions to medications.
    • Elevated scores on the MMPI psychotic tetrad were found in patients with adverse reactions to central stimulants and anorectics.

    Conclusions:

    • Childhood Sydenham's chorea may result in persistent sensitivity to dopaminergic-augmenting agents.
    • This sensitivity can manifest as acute chorea or psychological difficulties.
    • Central dopaminergic hypersensitivity may underlie reported psychologic issues in SC survivors.