Complexity of RNA from the neuronal and glial nuclei

The unique DNA expression value in the brain nuclear RNA was much higher than those from other tissues. The origin of this high complexity of brain nuclear RNA was examined using the [3H]DNA-RNA saturation hybridization technique. RNA was extracted from the isolated neuronal and glial nuclei. The experimental results may indicate that the high complexity in the brain nuclei does not result from the summation of many cell types but only from the neuronal nuclei.