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Frontal lobe calcification in hypoparathyroid states.

R A Bloom, D Rubinger, H Pogrund

    Journal of Neurology
    |January 1, 1983
    PubMed
    Summary

    Cerebral cortical calcification is rare in hypoparathyroid states, predominantly affecting the frontal lobes. This case highlights pseudohypoparathyroidism as a cause of this rare neurological finding.

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    Area of Science:

    • Neurology
    • Endocrinology
    • Radiology

    Background:

    • Basal ganglia calcification is a known complication of hypoparathyroid states.
    • Cerebral cortical calcification is an uncommon manifestation in these conditions.

    Observation:

    • This report details a rare case of cerebral cortical calcification in a patient with pseudohypoparathyroidism.
    • Previously, only six cases of cerebral cortical calcification in hypoparathyroidism were documented.

    Findings:

    • The patient presented with pseudohypoparathyroidism and significant cerebral cortical calcification.
    • Cortical calcification in this condition predominantly involves the frontal lobes.

    Implications:

    • This case underscores the importance of considering pseudohypoparathyroidism in patients with unexplained cerebral cortical calcification.
    • Further research may elucidate the specific mechanisms leading to frontal lobe predilection in these calcification patterns.

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