Chemical and pharmacokinetic considerations in structure-activity relationships: panel discussion

A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humans.

Journal of toxicology and environmental health. Part B, Critical reviews·2017

Early differential cell death and survival mechanisms initiate and contribute to the development of OPIDN: a study of molecular, cellular, and anatomical parameters.

Toxicology and applied pharmacology·2011

In vivo binding of [(14)C]acrylamide to proteins in the mouse nervous system.

Neurochemistry international·2010

Comparison of endogenous phosphorylation of hen and rat spinal cord proteins and partial characterization of optimal phosphorylation conditions for hen spinal cord.

Neurochemistry international·2010

In vitro metabolism and interactions of pyridostigmine bromide, N,N-diethyl-m-toluamide, and permethrin in human plasma and liver microsomal enzymes.

Xenobiotica; the fate of foreign compounds in biological systems·2008

The relationship of maternal and fetal toxicity in developmental toxicology bioassays with notes on the biological significance of the "no observed adverse effect level".

Reproductive toxicology (Elmsford, N.Y.)·2008

Combined Thermal Stress and Nanoplastic Exposure Induce Oxidative-Mediated Neurodevelopmental Toxicity and Behavioral Alterations in Zebrafish.

Neurotoxicology·2026

Chronic cocaine exposure disrupts cholinergic neuron integrity and function in organotypic slices of the laterodorsal tegmentum.

Neurotoxicology·2026

Curcumin attenuates acrylamide-induced cerebellar neurofilament accumulation, BDNF decline and motor dysfunction.

Neurotoxicology·2026

Effects of Micro- and Nanoplastic Exposure During Critical Developmental Periods on the Central Nervous System: A Systematic Review of Rodent Models.

Neurotoxicology·2026

Xylazine, veterinary anesthetic and recreational drug adulterant, reduces cephalic regeneration and alters defensive responding in planarians.

Neurotoxicology·2026

Firemaster 550 differentially alters gene expression underlying synaptic function in amygdala of prairie voles after gestational or lactational exposure.

Neurotoxicology·2026

Hepatotoxicity of Avacopan: Real-World Incidence and Confirmed Cases of Severe Drug-Induced Liver Injury in a US National Rheumatology Registry.

Arthritis & rheumatology (Hoboken, N.J.)·2026

Tail-aware heterogeneous graph neural networks for multi-class drug-drug interaction prediction.

Bioinformatics (Oxford, England)·2026

Corrigendum to: Synthesis, Pharmacological Activities, Structure-activity Relationship of 1,3,4-Oxadiazole-Piperazine Conjugates: A Review.

Medicinal chemistry (Shariqah (United Arab Emirates))·2026

Fuzzy Support Vector Regression for QSAR Modeling of 9,10-Dihydrophenanthrene Derivatives Against SARS-CoV-2 3CLpro.

Current computer-aided drug design·2026

Design, Synthesis, In Silico and In Vitro Analysis of Newly Synthesized 2-Mercaptobenzazole Derivatives as Potential Acetylcholinesterase Inhibitors.

Current medicinal chemistry·2026

QSAR Modeling of 1,3,4-Oxadiazole Derivatives for Predicting Anticancer Activity Using SO-PLS Analysis.

Current drug discovery technologies·2026

Related Experiment Videos

Chemical and pharmacokinetic considerations in structure-activity relationships: panel discussion

Related Concept Videos

A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humans.

Early differential cell death and survival mechanisms initiate and contribute to the development of OPIDN: a study of molecular, cellular, and anatomical parameters.

In vivo binding of [(14)C]acrylamide to proteins in the mouse nervous system.

Comparison of endogenous phosphorylation of hen and rat spinal cord proteins and partial characterization of optimal phosphorylation conditions for hen spinal cord.

In vitro metabolism and interactions of pyridostigmine bromide, N,N-diethyl-m-toluamide, and permethrin in human plasma and liver microsomal enzymes.

The relationship of maternal and fetal toxicity in developmental toxicology bioassays with notes on the biological significance of the "no observed adverse effect level".

Combined Thermal Stress and Nanoplastic Exposure Induce Oxidative-Mediated Neurodevelopmental Toxicity and Behavioral Alterations in Zebrafish.

Chronic cocaine exposure disrupts cholinergic neuron integrity and function in organotypic slices of the laterodorsal tegmentum.

Curcumin attenuates acrylamide-induced cerebellar neurofilament accumulation, BDNF decline and motor dysfunction.

Effects of Micro- and Nanoplastic Exposure During Critical Developmental Periods on the Central Nervous System: A Systematic Review of Rodent Models.

Xylazine, veterinary anesthetic and recreational drug adulterant, reduces cephalic regeneration and alters defensive responding in planarians.

Firemaster 550 differentially alters gene expression underlying synaptic function in amygdala of prairie voles after gestational or lactational exposure.

Hepatotoxicity of Avacopan: Real-World Incidence and Confirmed Cases of Severe Drug-Induced Liver Injury in a US National Rheumatology Registry.

Tail-aware heterogeneous graph neural networks for multi-class drug-drug interaction prediction.

Corrigendum to: Synthesis, Pharmacological Activities, Structure-activity Relationship of 1,3,4-Oxadiazole-Piperazine Conjugates: A Review.

Fuzzy Support Vector Regression for QSAR Modeling of 9,10-Dihydrophenanthrene Derivatives Against SARS-CoV-2 3CLpro.

Design, Synthesis, In Silico and In Vitro Analysis of Newly Synthesized 2-Mercaptobenzazole Derivatives as Potential Acetylcholinesterase Inhibitors.

QSAR Modeling of 1,3,4-Oxadiazole Derivatives for Predicting Anticancer Activity Using SO-PLS Analysis.

Related Experiment Videos

Chemical and pharmacokinetic considerations in structure-activity relationships: panel discussion

Related Concept Videos

Related Articles