Accumulation of 99mTc-diphosphonate in hepatic neoplasm

Bone images revealed excessive accumulation of radionuclide within a lesion in the liver which was suspected to be a metastasis from a primary carcinoma in the gastrointestinal tract. A "doughnut sign" of the liver with 99mTc-diphosphonate is rare, and the possibility of specific tumor uptake of this nuclide should be kept in mind.