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Updated: Aug 18, 2026

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
Hospital acquired rotaviral gastroenteritis in a general paediatric unit
Insights
Rotaviruses caused significant gastroenteritis in children, both in the community and within hospitals. Virucidal handwashing may prevent hospital-acquired rotavirus infections.
Area of Science:
- Pediatrics
- Infectious Diseases
- Hospital Epidemiology
Background:
- Acute gastroenteritis is a common pediatric illness.
- Hospital-acquired infections pose a significant risk to vulnerable patients.
- Rotavirus is a major cause of gastroenteritis in children.
Purpose of the Study:
- To investigate the incidence and sources of rotavirus infections in hospitalized children.
- To assess the effectiveness of current infection control measures against bacterial and viral pathogens.
- To explore potential strategies for preventing hospital-acquired rotaviral infections.
Main Methods:
- Retrospective analysis of pediatric admissions over a one-year period.
- Stool sample testing for rotavirus and bacterial pathogens.
- Evaluation of infection control practices, including barrier nursing.
Main Results:
- Rotaviruses were detected in 39% of community-acquired and 59% of hospital-acquired gastroenteritis cases.
- Bacterial stool pathogens were present, but spread was limited by barrier nursing.
- A higher proportion of hospital-acquired infections were attributed to rotavirus.
Conclusions:
- Rotavirus is a prevalent cause of gastroenteritis in hospitalized children.
- Barrier nursing effectively controlled bacterial spread but was less effective against rotavirus.
- Virucidal hand hygiene agents may be crucial in preventing hospital-acquired rotavirus transmission.
Abstract:
Between 1 October 1981 and 30 September 1982, 74 children with acute gastroenteritis were admitted to the paediatric wards at St Thomas' Hospital, and a further 37 patients acquired gastroenteritis while in hospital. Rotaviruses were detected in the stools of 29 of 74 (39 per cent) of patients with community-acquired and 22 of 37 (59 per cent) of patients with hospital-acquired infection. Although patients were also admitted with bacterial stool pathogens, barrier nursing techniques were apparently successful in preventing spread of these. The use of a virucidal agent for handwashing might be effective in preventing hospital-acquired rotaviral infections.
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