Ontogeny of polyamines in relation to nucleic acids in brain and spinal cord of the developing human fetus

The polyamines, spermine and spermidine, and the diamine, putrescine, were estimated in relation to the distribution of RNA and DNA in cerebral cortex, cerebellum and spinal cord of the human CNS during prenatal development. Polyamines were found to be maximally located in the spinal cord, minimum being in cerebellum. Relation between polyamines and nucleic acids was region specific.