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Multiple sclerosis with onset after age 60.

T R Marra

    Journal of the American Geriatrics Society
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Late-onset multiple sclerosis (MS) is rare, often delaying diagnosis in older adults. Early consideration and specific tests can aid in identifying MS in this population.

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    Area of Science:

    • Neurology
    • Geriatrics
    • Immunology

    Background:

    • Multiple sclerosis (MS) onset typically occurs in younger adults.
    • MS after age 60 is exceptionally rare, posing diagnostic challenges.

    Observation:

    • Three cases of late-onset MS (onset >60 years) are presented.
    • Symptoms were initially misattributed to common geriatric conditions.
    • Diagnostic delays were significant in all reported cases.

    Findings:

    • Clinical presentation of late-onset MS can mimic other age-related diseases.
    • Cerebral evoked potentials and CSF immunoglobulin studies can aid diagnosis.
    • MS should be considered in the differential diagnosis of elderly patients with neurological symptoms.

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    Implications:

    • Increased awareness of late-onset MS is crucial for timely diagnosis.
    • Utilizing specific neurophysiological and immunological tests can improve diagnostic accuracy.
    • Prompt MS diagnosis in older adults can lead to earlier treatment and better management.