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Behavioral change in a cancer patient following intrathecal beta-endorphin administration
The American Journal of Psychiatry
|January 1, 1984
Abstract:
A patient with a disseminated malignancy received 3 mg of synthetic beta-endorphin administered intrathecally by lumbar puncture. A marked behavioral syndrome characterized by confusion, hypomanic/manic behavior, and psychosis followed drug administration and persisted for more than 2 days.
