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[ACD-AG blood with decreased adenine and guanosine content]
Abstract:
ACD-AG blood with 2 different initial concentrations of adenine and guanosine--both 0.25 and 0.5 mmol/l, respectively--has been studied by using 13 parameters. Differences could not be found in 11 parameters, among them ATP and 2,3-P2G content and the number of microaggregates. The formation of lactate and the hemolyses rate were slightly increased during 6 weeks. But the mean hemolysis rate was below 1%. A sufficient maintenance of red cell metabolism at lower adenine and guanosine concentrations as found in ACD-AG blood can also be supposed for the preservation of buffy coat-free red cell concentrates.