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Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

S M Hedrick, D I Cohen, E A Nielsen

    Nature
    |March 8, 1984
    PubMed

    Of 10 distinct cloned DNA copies of mRNAs expressed in T lymphocytes but not in B lymphocytes and associated with membrane-bound polysomes, one hybridizes to a region of the genome that has rearranged in a T-cell lymphoma and several T-cell hybridomas. These characteristics suggest that it encodes one chain of the elusive antigen receptor on the surface of T lymphocytes.

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