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Updated: Jul 20, 2026

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
Published on: May 4, 2012
Complexes of acid alpha 1-glycoprotein with immunoglobulins G in normal human blood serum
Abstract:
DEAE-cellulose chromatography was applied for isolation of the complexes of acid alpha 1-glycoprotein (alpha 1-AGP) with immunoglobulins G (IgG). The heterogeneous glycoprotein fraction V was found to contain 75% of total alpha 1-AGP complexed with IgG3, as identified by Protein A-Sepharose chromatography. The results obtained indicate that in normal blood serum 30% of IgG3 and 75% of alpha 1-AGP are bound in the IgG3 - alpha 1-AGP complexes, whereas the remaining parts of IgG3 and alpha 1-AGP are present in free form.
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