Related Experiment Video

Updated: Aug 10, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

[Long-term fate of very-low-birth-weight children]

F Cukier-Hemeury, G Moriette, C Bordarier

    Archives Francaises De Pediatrie
    |January 1, 1984
    PubMed

    Insights

    Most extremely low birth weight infants who survive intensive care experience developmental outcomes, with early screening and intervention improving long-term prognosis for these high-risk neonates.

    Area of Science:

    • Neonatal intensive care
    • Pediatric neurology
    • Developmental pediatrics

    Context:

    • Extremely low birth weight (ELBW) infants (≤1,250 g) face significant risks.
    • Neonatal intensive care unit (NICU) admissions highlight the vulnerability of these infants.
    • Long-term neurodevelopmental outcomes require thorough investigation.

    Purpose:

    • To assess the neurodevelopmental outcomes of ELBW infants followed up for approximately 4 years.
    • To identify risk factors and patterns of sequelae in this high-risk population.
    • To evaluate the feasibility of early screening and the role of prenatal factors.

    Summary:

    • Of 75 ELBW neonates admitted, 34 were followed up. 44% were normal, 35% had minor sequelae, 14.7% moderate, and 6% major sequelae.
    • No cases of hydrocephalus, severe encephalopathy, deafness, or blindness were observed.
    • Growth retardation affected 12 children; all with sequelae had significant neonatal neurological involvement.

    Impact:

    • Early identification of neurodevelopmental disorders in ELBW survivors is possible.
    • Antenatal and maternal factors are crucial for predicting neonatal risks.
    • Improved obstetrician-pediatrician collaboration can optimize management for ELBW premature infants.

    More Related Videos

    Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats07:36

    Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

    Published on: November 20, 2015

    A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis06:19

    A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

    Published on: January 7, 2018

    Related Concept Videos

    Regression Toward the Mean01:52

    Regression Toward the Mean

    Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
    Teratogenicity01:07

    Teratogenicity

    The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
    Pathophysiology of Diabetes01:20

    Pathophysiology of Diabetes

    Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
    Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
    Development of the Oral Microbiota01:28

    Development of the Oral Microbiota

    The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...