Morphological study of the reticular erythematous mucinosis syndrome

Histopathological studies were conducted on skin biopsies of 4 patients with the reticular erythematous mucinosis (REM) syndrome. The diagnosis was made on the basis of the clinical picture in 3 of the cases and from histological characteristics in the 4th. These morphological studies were done parallel with a study of skin biopsies with quite a similar histological picture but in which the clinical picture clearly indicated differing entities. The nosologic place of REM syndrome is questioned and the impression arises that there is a clear-cut histogenetical connection with several inflammatory skin diseases.