Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A nonhuman primate model of risk for deviant development.

G P Sackett

    American Journal of Mental Deficiency
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Self-injurious behavior: gene-brain-behavior relationships.

    Mental retardation and developmental disabilities research reviews·2001
    Same author

    Weaning, body weight, and postpartum amenorrhea duration in pigtailed macaques (Macaca nemestrina).

    American journal of primatology·2000
    Same author

    Demographic analysis of the washington regional primate research center pigtailed macaque colony, 1967-1996.

    American journal of primatology·2000
    Same author

    Social housing and pregnancy outcome in captive pigtailed macaques.

    American journal of primatology·1999
    Same author

    Behavioral measurement of temperament in male nursery-raised infant macaques and baboons.

    American journal of primatology·1999
    Same author

    Fetal, infant, and maternal toxicity of zidovudine (azidothymidine) administered throughout pregnancy in Macaca nemestrina.

    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association·1998

    This study introduces a nonhuman primate model to investigate developmental delays. Findings reveal that both maternal and paternal factors significantly influence offspring development, impacting various systems.

    Area of Science:

    • Developmental biology
    • Primate research
    • Behavioral genetics

    Background:

    • Complex factors including genetic, prenatal, perinatal, and postnatal influences can cause developmental delays and permanent intellectual disability.
    • Studying human developmental systems experimentally is challenging due to ethical constraints and confounding variables.
    • Animal models offer a viable alternative for investigating developmental processes.

    Purpose of the Study:

    • To describe a nonhuman primate model for studying developmental delays.
    • To examine the impact of parental risk factors on offspring development.
    • To investigate genetic, physiological, and psychosocial influences on delayed development.

    Main Methods:

    • Utilized pigtailed monkeys (Macaca nemestrina) as a nonhuman primate model.

    Related Experiment Videos

  • Focused on offspring from high- and low-risk breeders.
  • Subjects were nursery-reared without postnatal parental contact to isolate parental effects.

    • Main Results:

    • Both maternal and paternal factors were associated with delayed development in offspring.
    • Developmental delays were observed across a range of systems, from tooth eruption to concept learning.
    • The model demonstrated the influence of parental risk on various developmental outcomes.

    Conclusions:

    • Parental factors play a crucial role in offspring development, even in the absence of direct postnatal contact.
    • The nonhuman primate model effectively elucidates the complex interplay of factors contributing to developmental delays.
    • This research provides insights into the biological and environmental underpinnings of developmental trajectories.