The ultrastructure of chondroid syringoma (mixed tumor of skin)

The ultrastructural features of a chondroid syringoma (mixed tumor of skin) are presented. The tumor consisted of groups of epithelial cells, ductal structures, and cells lying individually within a cartilaginous matrix. Many of these latter cells were indistinguishable morphologically from true chondrocytes. Some of these chondroid cells showed positive staining for cytokeratin using the immunoperoxidase technique. Transitional cells with characteristics intermediate between epithelial and chondroid cells are noted.