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Functional analogs of bleomycin: sequence-specific DNA cleavage with porphyrin (Fe) intercalators
Gan
|July 1, 1984
Abstract:
Synthetic porphyrin (Fe) intercalators cleave DNA at guanine-cytosine and guanine-thymine sequences. The specificity for cleavage of base sequences of DNA is quite similar to that of bleomycin.
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