[Possibilities of using ferromagnetic materials for targeted drug transport]

Possibilities of using particles containing ferromagnetic materials and magnetic concentrated colloids for targeted drug transport have been studied. Magnetic particles produced from Sephadex G-25 by ferromagnetic material fixation, polymer-modified iron particles 100 nm in diameter, and concentrated colloid solutions of Fe3O4 are retained in the marginal ear vein of the rabbit by magnetic field at H = 0.5 kHs/cm. The data on magnetic retention of the above-indicated agents in the vein, obtained by measuring 75Se and 131I activity, of labeled particles are presented.