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Elevation of serum prostatic acid phosphatase levels after prostatic massage
Urology
|December 1, 1984
Summary
Prostatic massage significantly increases serum prostatic acid phosphatase (PAP) levels in most benign prostatic hyperplasia patients. However, this elevation rarely returns PAP levels to normal ranges in these patients.
Area of Science:
- Urology
- Andrology
- Clinical Chemistry
Background:
- Benign prostatic hyperplasia (BPH) and prostatic carcinoma (CA) are common conditions affecting the prostate gland.
- Serum prostatic acid phosphatase (PAP) is a biomarker associated with prostate health.
Purpose of the Study:
- To investigate the impact of prostatic massage on serum PAP levels in patients with BPH and CA.
- To assess whether prostatic massage can normalize elevated PAP levels.
Main Methods:
- Serum PAP levels were measured using radioimmunoassay (RIA).
- Prostatic massage was performed on 29 BPH patients and 7 CA patients.
- Post-massage PAP levels were compared to pre-massage levels.
Main Results:
- A significant increase in post-massage PAP levels was observed in 77% of BPH patients (P < 0.001).
- Only 10% of BPH patients experienced a normalization of PAP levels after massage.
- Data for CA patients was not detailed in the provided abstract.
Conclusions:
- Prostatic massage demonstrably elevates serum PAP levels in the majority of BPH patients.
- The therapeutic effect of prostatic massage in normalizing PAP levels in BPH is limited.