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Related Experiment Videos

[Prophylactic cefmetazole in transurethral prostatectomy].

K Fujita, M Sugimoto, T Hara

    The Japanese Journal of Antibiotics
    |September 1, 1984
    PubMed
    Summary

    Cefmetazole effectively treated preoperative bacteriuria in transurethral prostatectomy patients. Most infections cleared, preventing postoperative complications like epididymitis or fever.

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    Tissue-specific alternative splicing of the first exon generates two types of mRNAs in human aromatic L-amino acid decarboxylase.

    Biochemistry·1992

    Area of Science:

    • Urology
    • Infectious Diseases
    • Pharmacology

    Context:

    • Transurethral prostatectomy (TURP) is a common urological procedure.
    • Preoperative bacteriuria poses a risk for postoperative infections in TURP patients.

    Purpose:

    • To evaluate the efficacy of cefmetazole in treating preoperative bacteriuria in patients undergoing transurethral prostatectomy.
    • To assess the incidence of postoperative infectious complications.

    Summary:

    • Patients received cefmetazole (2g twice daily on day 1, then once daily for 2 days).
    • Out of 34 cases, 13 had significant preoperative bacteriuria.
    • Bacteriuria persisted in only 3 patients by day 5 post-treatment.
    • All patients experienced uneventful postoperative courses, with no acute epididymitis or significant fever.

    Impact:

    • Cefmetazole demonstrates significant efficacy in eradicating preoperative bacteriuria in TURP patients.
    • This prophylactic regimen appears to reduce the risk of postoperative infectious complications, contributing to better patient outcomes.

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