Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Meleda disease - akroerythrokeratoderma].

T Salamon, B Cezarović, M Nardelli-Kovacici

    Zeitschrift Fur Hautkrankheiten
    |April 15, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Extended Bose-Hubbard model with dipolar excitons.

    Nature·2022
    Same author

    [To Prof. Dr. Dr. h.c. mult. Otto Braun-Falco: Birthday wishes and expression of appreciation from the Swiss Society for Dermatology and Venereology (SGDV)].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2012
    Same author

    Endovascular repair of ruptured aortic penetrating ulcer via carotid artery.

    Annals of vascular surgery·2008
    Same author

    Nail changes in epidermolysis bullosa: clinical and pathogenetic considerations.

    The British journal of dermatology·1995
    Same author

    A contribution to the understanding of the heredity of skin tumors.

    The Journal of dermatology·1994
    Same author

    The MNSs and Kk blood group systems in the disease of Mljet (mal de Meleda)

    Dermatology (Basel, Switzerland)·1994
    Same journal

    [Acne vulgaris: morphologic, endocrinologic and psychosomatic aspects].

    Zeitschrift fur Hautkrankheiten·1990
    Same journal

    [Anti-androgen treatment of hirsutism with cyproterone acetate].

    Zeitschrift fur Hautkrankheiten·1990
    Same journal

    [Changes in sunscreening products in West Germany between 1988 and 1989/90].

    Zeitschrift fur Hautkrankheiten·1990
    Same journal

    [Effect of treatment with salt from the Dead Sea (Tomesa therapy) on epidermal Langerhans cells--a clinical study].

    Zeitschrift fur Hautkrankheiten·1990
    Same journal

    [DNA determination by cytophotometry in bowenoid papules in comparison with condylomata acuminata and Bowen's disease].

    Zeitschrift fur Hautkrankheiten·1990
    Same journal

    [Adverse drug reactions on hair].

    Zeitschrift fur Hautkrankheiten·1990
    See all related articles

    Meleda disease, a type of Akroerythrokeratodermia, involves hyperkeratosis and erythrodermatic signs. Aromatic retinoid treatment significantly reduced hyperkeratosis within two weeks.

    Area of Science:

    • Dermatology
    • Genetics
    • Rare Diseases

    Context:

    • Meleda disease is a rare genetic skin disorder.
    • Patients present with distinct hyperkeratosis and erythrodermatic signs.
    • The condition is endemic to the island of Mljet (Meleda).

    Purpose:

    • To reexamine clinical characteristics of Meleda disease.
    • To investigate the efficacy of aromatic retinoid treatment.
    • To classify Meleda disease within the Akroerythrokeratodermia group.

    Summary:

    • Eight patients with autochthonous Meleda disease were reexamined, with three additional cases from Mljet reported.
    • Clinical findings suggest Meleda disease belongs to the Akroerythrokeratodermias group.
    • Treatment with an aromatic retinoid (Ro 10-9359) led to a drastic reduction in hyperkeratosis within two weeks, while erythrodermatic signs were less affected.

    Related Experiment Videos

    Impact:

    • Provides clinical insights into Meleda disease.
    • Demonstrates the therapeutic potential of aromatic retinoids for hyperkeratosis.
    • Contributes to the classification of rare dermatological disorders.