Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fetal dermatoglyphics.

M B Katznelson, B Goldman

    Clinical Genetics
    |April 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Dermatoglyphic analysis of aborted embryos revealed significant deviations in fingertip and palm patterns. These dermatoglyphic findings correlated with chromosomal abnormalities, aiding in genetic diagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Recombinant long-acting glycoPEGylated factor IX (nonacog beta pegol) in haemophilia B: assessment of target joints in multinational phase 3 clinical trials.

    Haemophilia : the official journal of the World Federation of Hemophilia·2016
    Same author

    A global cloud map of the nearest known brown dwarf.

    Nature·2014
    Same author

    Limitations of sniff nasal pressure as an outcome measurement in amyotrophic lateral sclerosis patients in a clinical trial.

    Respiration; international review of thoracic diseases·2012
    Same author

    Southwest Oncology Group study S0413: a phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer.

    Annals of oncology : official journal of the European Society for Medical Oncology·2011
    Same author

    Part II: The Difficult Patient Detecting Drug Seekers in Primary Care.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Computers in Primary Care Teaching: New software can help train residents to diagnose and treat illness.

    Canadian family physician Medecin de famille canadien·2011
    Same journal

    Genetic Spectrum of Non-PTPN11 Variants in Noonan Syndrome and Related RASopathies: Findings From a Russian Cohort.

    Clinical genetics·2026
    Same journal

    Phenotypic Characterization of Five Children With PACS1-NDD: Longitudinal Insights Into Development, Behavior, and Brain.

    Clinical genetics·2026
    Same journal

    A Second Report of a Missense Variant in AMMECR1 Causing Midface Hypoplasia, Hearing Impairment, Elliptocytosis, and Nephrocalcinosis: Case Report and Literature Review.

    Clinical genetics·2026
    Same journal

    From Pathogenicity to Mechanism: A Variant Interpretation Framework for Monogenic Epilepsy.

    Clinical genetics·2026
    Same journal

    Biallelic Variants in ATP1A4 Are Associated with Oligoasthenoteratozoospermia and Male Infertility.

    Clinical genetics·2026
    Same journal

    Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy.

    Clinical genetics·2026
    See all related articles

    Area of Science:

    • Human Embryology
    • Genetics
    • Dermatoglyphics

    Background:

    • Chromosomal aberrations are a significant cause of spontaneous abortions.
    • Dermatoglyphics, the study of skin patterns, can offer insights into developmental abnormalities.

    Purpose of the Study:

    • To investigate dermatoglyphic patterns in human embryos with known chromosomal aberrations.
    • To determine the correlation between dermatoglyphic deviations and specific cytogenetic diagnoses.

    Main Methods:

    • Dermatoglyphic prints were obtained from 24 aborted human embryos using the Hollister method.
    • Analysis included fingertip patterns, atd angle measurement, and palm/foot pattern classification (Penrose system).
    • Cytogenetic diagnoses were previously established via amniocentesis.

    Related Experiment Videos

    Main Results:

    • Twenty-two out of 24 embryos exhibited dermatoglyphic deviations.
    • These deviations showed a strong correlation with the identified cytogenetic diagnoses.
    • Specific aberrations included trisomy 21 (7 embryos), trisomy 18 (2), trisomy 13 (2), structural autosomal aberrations (3), and sex-chromosome aberrations (10).

    Conclusions:

    • Dermatoglyphic analysis is a valuable tool for identifying developmental anomalies in human embryos.
    • Skin pattern deviations can serve as indicators for underlying chromosomal abnormalities.
    • This study highlights the utility of dermatoglyphics in prenatal genetic diagnostics.