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Abnormal visual-evoked responses and opsoclonus.

B Jabbari, E Urban

    Journal of Clinical Neuro-Ophthalmology
    |December 1, 1981
    PubMed
    Summary
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    A 73-year-old woman experienced opsoclonus after a febrile illness, showing abnormal visual evoked response (VER) tests that normalized over time. This case highlights the transient nature of post-infectious neurological symptoms and VER changes.

    Area of Science:

    • Neuro-ophthalmology
    • Neurology
    • Infectious Diseases

    Background:

    • Opsoclonus, a rare neurological disorder characterized by involuntary, rapid, conjugate eye movements, can occur post-infection.
    • Acute febrile illnesses can sometimes trigger paraneoplastic or post-infectious neurological syndromes.

    Observation:

    • A 73-year-old woman developed opsoclonus two weeks after an acute febrile illness.
    • Clinical recovery was noted four weeks later, with abnormal eye movements resolving.
    • Visual evoked response (VER) testing six weeks after onset revealed delayed responses and high amplitude in both eyes.

    Findings:

    • The patient reported intermittent blurred vision for two months following the resolution of opsoclonus.
    • A follow-up VER test four months after symptom onset showed normalized latency and amplitude.

    Related Experiment Videos

  • The study discusses potential mechanisms underlying the transient visual evoked response abnormalities.

    • Implications:

    • This case suggests that post-infectious opsoclonus can be associated with temporary visual pathway dysfunction.
    • Serial neurophysiological testing, such as VER, may be valuable in monitoring recovery from such neurological events.
    • Understanding these transient changes aids in diagnosing and managing post-infectious neurological sequelae.