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Updated: Aug 18, 2026
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Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
Published on: December 3, 2016
A biochemical and morphological investigation of alkaline phosphatase and Ca+2-ATPase during initial mineralization
The Journal of Experimental Zoology
|July 1, 1982
Abstract:
Biochemical analysis of the enzymes alkaline phosphatase and Ca+2-ATPase in the membrane fraction obtained from chick embryonic tibias showed a positive correlation between the elevated activity of these two enzymes and the onset of mineralization. Histochemistry further showed an increased intensity of alkaline phosphatase at the time of the onset of mineralization. It seems that both of these enzymes are involved in the process of mineralization.
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The calcium concentration in blood plasma is primarily regulated...
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