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[The psoriatic bone manifestation].

H Holzmann, D Eissner, K Hahn

Zeitschrift Fur Hautkrankheiten

|August 1, 1982

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Skeletal scintigraphy in psoriasis patients revealed abnormal radionuclide uptake in non-joint bone areas. This suggests proliferative bone changes related to collagen metabolism alterations in psoriatic disease.

Area of Science:

Nuclear Medicine
Dermatology
Orthopedics

Background:

Psoriasis is a chronic inflammatory disease with known joint involvement.
Whole-body scans using 99m technetium-phosphate-complexes (TcP) typically assess joint pathology.

Purpose of the Study:

To investigate skeletal scintigraphic findings beyond joint regions in patients with psoriasis.
To explore potential bone proliferative phenomena associated with psoriasis.

Main Methods:

Skeletal scintigraphy was performed on 17 patients with psoriasis.
99m technetium-phosphate-complexes (TcP) were used to visualize bone.
Radionuclide accumulation in skull, thyroid cartilage, bony thorax, and long bones was analyzed.

Main Results:

Related Experiment Videos

Pathological concentrations of TcP were observed in non-joint skeletal areas.
These findings included skull, thyroid cartilage, bony thorax, and long bones.
The radionuclide accumulation was circumscribed or diffuse.

Conclusions:

Psoriasis may be associated with proliferative bone changes.
Abnormal TcP accumulation distant from joints suggests altered collagen metabolism in psoriatic bone.
Skeletal scintigraphy can reveal non-articular bone involvement in psoriasis.