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GLC determination of phenylbutazone in human plasma

A Sioufi, F Caudal, F Marfil

Journal of Pharmaceutical Sciences

|February 1, 1978

Abstract:

A GLC method for phenylbutazone at concentrations down to 10 ng/ml in human plasma is described. After addition of an internal standard, phenylbutazone is extracted at pH 5 into benzene. The dry extract is dissolved in benzene, and phenylbutazone is determined by GLC using a 63Ni-electron-capture detector.

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