Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Murine renal cell carcinoma: a suitable human model.

G P Murphy

    Progress in Clinical and Biological Research
    |January 1, 1982
    PubMed
    Summary

    A new mouse model for metastatic renal adenocarcinoma was studied for tumor growth and chemotherapy response. This model offers insights relevant to human renal cell carcinoma research.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Two mechanisms for growth inhibition by elevated transport of sugar phosphates in Escherichia coli.

    Journal of general microbiology·1992
    Same author

    Revision in American Cancer Society recommendations for the early detection of colorectal cancer.

    CA: a cancer journal for clinicians·1992
    Same author

    The association of benign prostatic hyperplasia and cancer of the prostate.

    Cancer·1992
    Same author

    Relapsing disease.

    Cancer·1992
    Same author

    The relationship of prostate-specific antigen to digital rectal examination and transrectal ultrasonography. Findings of the American Cancer Society National Prostate Cancer Detection Project.

    Cancer·1992
    Same author

    Prostate-specific antigen levels in 1695 men without evidence of prostate cancer. Findings of the American Cancer Society National Prostate Cancer Detection Project.

    Cancer·1992

    Area of Science:

    • Oncology
    • Animal Models

    Background:

    • Renal cell carcinoma (RCC) research utilizes various animal models.
    • A specific metastatic renal adenocarcinoma model in BALB/c mice is favored for its study potential.

    Purpose of the Study:

    • To characterize tumor kinetics in a metastatic renal adenocarcinoma mouse model.
    • To evaluate the effects of chemotherapy and other interventions in this model.
    • To compare this model with other available renal cell carcinoma models.

    Main Methods:

    • Serial transplantation of a metastatic renal adenocarcinoma in BALB/c mice.
    • Monitoring of tumor growth and kinetics.
    • Assessment of chemotherapy efficacy and other experimental manipulations.

    Main Results:

    • Detailed kinetics of tumor progression were established.
    • The model demonstrated responsiveness to chemotherapy, with observed effects.
    • The study provides a basis for further investigation into therapeutic strategies.

    Conclusions:

    • The metastatic renal adenocarcinoma model in BALB/c mice is a valuable tool for studying renal cell carcinoma.
    • This model facilitates research into tumor behavior and treatment efficacy relevant to human patients.

    Related Experiment Videos