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Bilateral renal cell carcinoma.

D E Johnson, A Voneschenbach, J Sternberg

    The Journal of Urology
    |January 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Conservative treatment for bilateral renal cell carcinoma may be effective, even with incomplete excision. Radical surgery requiring dialysis or transplantation is rarely necessary for these kidney cancer patients.

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    Area of Science:

    • Nephrology
    • Oncology
    • Surgical Pathology

    Background:

    • Bilateral renal cell carcinoma (RCC) presents a complex clinical challenge.
    • Simultaneous or sequential diagnoses of bilateral RCC require careful management strategies.

    Purpose of the Study:

    • To evaluate the outcomes of conservative management versus radical excision for bilateral renal cell carcinoma.
    • To determine the necessity of aggressive surgical interventions like nephrectomy, dialysis, or transplantation in managing bilateral kidney tumors.

    Main Methods:

    • Retrospective analysis of 10 patients diagnosed with bilateral renal cell carcinoma.
    • Comparison of outcomes between patients treated with conservative incomplete excision and those undergoing radical excision.

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    Main Results:

    • Four patients treated conservatively with incomplete excision survived 18 months to 14 years post-diagnosis.
    • Radical excision, necessitating renal dialysis or transplantation, was required in a limited number of cases.

    Conclusions:

    • Conservative management with incomplete excision can lead to long-term survival in select bilateral renal cell carcinoma cases.
    • Radical surgical approaches for bilateral renal cell carcinoma are infrequently warranted, suggesting a paradigm shift towards less invasive treatments.