Peculiarities of adaptation to systematic muscular activity in adrenalectomized rats

A 3 week training period in running restored the maximal swimming time of adrenalectomized rats to the level of intact untrained rats, but had no influence on the maximal running time and hepatic glycogen reserve. The cardiac hypertrophy and the augmentation of the Mg2+-activated ATPase activity of myocardium in adrenalectomized rats were more pronounced than in intact animals. It is concluded that the deficiency of adrenocortical hormones does not exclude all the adaptive alterations during training, although it makes the complete adaptation and normal increase of the working capacity impossible.