Related Experiment Video
Updated: Jul 1, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Is relaxation really impaired in cardiac failure?
Abstract:
Impaired relaxation of the ventricle has been described in hypertrophy and in ischemic heart disease. Some of these abnormalities are transient, but all occur at an early stage of the disease. The underlying mechanisms may vary depending on the etiology of the disease, and, except for ischemic heart disease, true myocardial impaired relaxation, as manifested by a suppressed load dependence, could not be demonstrated even at a stage when manifest cardiac failure is already present.
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