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Updated: Aug 17, 2026

Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
[Asymmetric hypertrophy of the myocardium in patients with hypertension (echocardiographic data)]
Insights
Asymmetrical hypertrophy of the ventricular septum, a condition seen in hypertensive disease, can be diagnosed using echocardiography. This condition affects myocardial function and can lead to left ventricular outflow tract obstruction, detectable with a nitroglycerin test.
Area of Science:
- Cardiology
- Medical Imaging
- Hypertension Research
Context:
- Hypertensive disease is a common condition with various cardiovascular complications.
- Asymmetrical hypertrophy of the ventricular septum (AHVS) is a specific manifestation within hypertensive heart disease.
- Echocardiography is a key diagnostic tool in cardiovascular medicine.
Purpose:
- To detail the diagnostic utility of echocardiography for identifying asymmetrical hypertrophy of the ventricular septum in hypertensive patients.
- To investigate the impact of AHVS on myocardial function and left ventricular (LV) outflow tract.
- To evaluate the effectiveness of the nitroglycerin test in revealing functional obstruction in AHVS.
Summary:
- Asymmetrical hypertrophy of the ventricular septum was observed in 4-5% of hypertensive patients.
- Echocardiographic findings indicate preserved contractile function but affected dilatation in these patients.
- A nitroglycerin test can reveal functional signs of LV outflow tract obstruction in individuals with AHVS.
Impact:
- This study enhances the understanding of AHVS diagnosis and its functional consequences in hypertensive disease.
- It highlights echocardiography's role in detecting subtle cardiac changes.
- The findings may inform clinical management strategies for hypertensive patients with septal hypertrophy and outflow obstruction.
Abstract:
This paper is devoted to the diagnosis of asymmetrical hypertrophy of the ventricular septum in patients with hypertensive disease with the aid of echocardiography. Asymmetrical hypertrophy of the ventricular septum comprised 4-5% of cases. The contractile function of the myocardium in this group of patients remains normal for a long time, while the dilatation is affected. The nitroglycerin test permits to elicit functional signs of obstruction to the outflow tract of the left ventricle in patients with asymmetrical hypertrophy of the ventricular septum.
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