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Updated: Aug 16, 2026

Measurement of Calcium Fluctuations Within the Sarcoplasmic Reticulum of Cultured Smooth Muscle Cells Using FRET-based Confocal Imaging
Published on: June 20, 2016
Sarcoplasmic reticulum vesicles from trembler mice: a comparison with material obtained from normal animals
Abstract:
Sarcoplasmic reticulum (SR) vesicles were purified from trembler and normal mice. Comparison of their chemical composition showed that the only differences lay in their phospholipid content, the most obvious modification being the presence of lysophosphatidylcholine in preparations obtained from trembler animals. A significant increase of the Ca2+-stimulated ATPase activity promoted a drastic loss in the efficiency of the calcium pumping system of the membrane purified from trembler mice. It is suggested that the modification of the phospholipid content might explain this effect.

