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Updated: Aug 16, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
Published on: August 13, 2017
[Biological behavior of a vascularized cortical bone graft. Experimental study of the rabbit fibula]
Abstract:
The study of the biological course of a vascularized osseous graft was performed on 64 fibulae in rabbits. Using radiography, standard histology, tetracyclines markage and study of 47-calcium incorporation as means of control. The time-limits of control are fixed at the 5th, 10th, 15th and 21st day and at the 1st, 2nd, 3rd and 5th month. The results show that if they are vascularized or not, the osseous grafts are not subjected to the rule: everything or nothing: "everything is not living in a vascularized osseous graft and everything is not dying in a conventional osseous graft". As for the good quality of the recipient bed, there is no significant difference between the healing time of those two types of grafts.
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