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Focal acral hyperkeratosis.

P M Dowd, R R Harman, M M Black

    The British Journal of Dermatology
    |July 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Fifteen cases of focal acral hyperkeratosis, clinically resembling acrokeratoelastoidosis (AKE), were identified. Histological differences, specifically the absence of elastorrhexis, distinguish this distinct skin condition.

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    Area of Science:

    • Dermatology
    • Histopathology

    Background:

    • Acrokeratoelastoidosis (AKE) is characterized by focal hyperkeratosis and elastorrhexis.
    • Clinical presentation of AKE can vary, posing diagnostic challenges.

    Purpose of the Study:

    • To describe a series of cases with clinical features similar to AKE.
    • To differentiate a newly proposed condition, focal acral hyperkeratosis, from AKE based on histological findings.

    Main Methods:

    • Clinical examination of fifteen patients presenting with focal acral hyperkeratosis.
    • Histopathological analysis of skin biopsies to identify key structural differences.

    Main Results:

    • All fifteen cases exhibited focal acral hyperkeratosis.
    • Clinically, the condition mimicked AKE.

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  • Histopathology revealed an absence of elastorrhexis, a hallmark of AKE.

    • Conclusions:

    • Focal acral hyperkeratosis represents a distinct clinical and histological entity.
    • The absence of elastorrhexis is a key differentiating feature from acrokeratoelastoidosis.