[Oral nickel administration in sensitized individuals]

A capsule containing nickel sulphate (2,8 or 5,6 mg Ni) was given to 43 women with nickel contact allergy. They were all observed 24 hours later. In 9 patients no reaction was seen. Thirty-four had positive reactions: in 27 a flare up of previously affected areas of contact, in 8 patients pompholyx eczema type of the hands was observed, 23 complained of pruritus, secondary eruptions and in 4 even urticarial rush. Similar study was performed in a control group of 10 women, without any reactions. The authors compare the results of this study with others previously reported.